Circadian Variations in Liver Gene Expression: Relationships to Drug Actions
نویسندگان
چکیده
Department of Biological Sciences, State University of New York at Buffalo, Buffalo, NY 14260 (RRA, WL, DCD) Department of Pharmaceutical Sciences, State University of New York at Buffalo, Buffalo, NY 14260 (RRA, DCD, WJJ) New York State Center of Excellence in Bioinformatics and Life Sciences (RRA, WJJ) Biomedical Engineering Department, Rutgers University Piscataway, NJ 08854 (EY, IA) JPET Fast Forward. Published on June 18, 2008 as DOI:10.1124/jpet.108.140186
منابع مشابه
Circadian variations in rat liver gene expression: relationships to drug actions.
Chronopharmacology is an important but under-explored aspect of therapeutics. Rhythmic variations in biological processes can influence drug action, including pharmacodynamic responses, due to circadian variations in the availability or functioning of drug targets. We hypothesized that global gene expression analysis can be useful in the identification of circadian-regulated genes involved in d...
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تاریخ انتشار 2008